Study Reveals Trauma’s Role in Mental Health Risk

A new study published in Biological Psychiatry: Global Open Science provides compelling evidence that trauma exposure plays a critical role in the link between psychiatric family history and mental health struggles in adolescents. Led by Dr. Barbara Chaiyachati and a team of researchers at the Children’s Hospital of Philadelphia, the study emphasizes trauma as a “modifiable risk factor in youth,” drawing attention to the environmental, rather than purely genetic, dimensions of intergenerational mental health.

“[I]n a large cohort of American adolescents,” the authors write, “trauma is more common among youth with [family history] of psychiatric disorders, and that over 20% of the risk association between [family history] and adolescent general psychopathology is mediated through trauma exposure.”

By demonstrating that nearly a quarter of the link between psychiatric family history and adolescent mental health struggles is mediated by trauma exposure, the research disrupts assumptions that genetic inheritance is the primary engine of psychopathology. Instead, it highlights how social and relational injuries, often shaped by caregiving dynamics, structural inequality, and intergenerational stress, embed themselves in psychological development.